Influenza Virus Net is the web resource for anyone interested in influenza and flu pandemics. Influenza, commonly referred to as the flu, is an infectious disease caused by RNA viruses of the family Orthomyxoviridae (the influenza viruses), that affects humans, birds and other mammals. The virus spreads easily from person to person. Influenza circulates worldwide and can affect anybody in any age group. Influenza causes annual epidemics that peak during winter in temperate regions. Influenza is a serious public health problem that causes severe illnesses and deaths for higher risk populations. The most common symptoms of the disease are chills, fever, sore throat, muscle pains, severe headache, coughing, weakness/fatigue and general discomfort. Sore throat, fever and coughs are the most frequent symptoms. In more serious cases, influenza causes pneumonia, which can be fatal, particularly for the young and the elderly. An influenza epidemic can take an economic toll through lost workforce productivity, and strain health services. Vaccination is the most effective way to prevent infection.

The objectives of Influenza Virus Net are to be the public and professional information resource for influenza and to serve as a network in the exchange of information and news related to influenza.

• Swine Influenza Detected in Jackson County - West Virginia Department of Health and Human Resources
  Wed, 03 Aug 2022 21:09 GMT
• Seeking Answers to Optimizing Influenza Vaccines in Older Adults through New Study - UConn Today - UConn
  Wed, 03 Aug 2022 16:30 GMT
• Vaxess starts Phase 1 trial for H1 influenza vaccine patch - BioPharma-Reporter.com
  Thu, 04 Aug 2022 11:26 GMT
• Faces of the Global Influenza Surveillance and Response System (GISRS) - World Health Organization
  Thu, 28 Jul 2022 11:24 GMT
• New Universal Flu Vaccine Protects Against Influenza B Viruses - Technology Networks
  Mon, 11 Jul 2022 07:00 GMT
• What's Coming in the 2022-2023 Flu Season - Drug Topics
  Thu, 04 Aug 2022 16:09 GMT
• What were the drivers of influenza decline during the COVID-19 pandemic? - News-Medical.Net
  Tue, 19 Jul 2022 07:00 GMT
• A combined influenza and COVID-19 mRNA vaccine - News-Medical.Net
  Thu, 04 Aug 2022 01:54 GMT
• Coinfection with Influenza A, SARS-CoV-2 May Suppress COVID-19 Severity, According to Study - Pharmacy Times
  Thu, 21 Jul 2022 07:00 GMT
• Influenza Activity and Vaccine Effectiveness During the 2021-2022 Season - Pharmacy Times
  Mon, 18 Jul 2022 07:00 GMT
• CDFW News | Avian Influenza Virus Detected in Wild Birds in California - California Department of Fish and Wildlife
  Thu, 14 Jul 2022 07:00 GMT
• Canine influenza cases now in Middle Tennessee - WKRN News 2
  Thu, 04 Aug 2022 23:12 GMT
• An inactivated multivalent influenza A virus vaccine is broadly protective in mice and ferrets - Science
  Wed, 13 Jul 2022 18:10 GMT
• Afghanistan influenza surveillance system stands solid - World Health Organization
  Fri, 29 Jul 2022 20:28 GMT
• Coinfection with influenza A could suppress replication in SARS-CoV-2, study shows - Science Daily
  Tue, 12 Jul 2022 07:00 GMT

• PRO/AH/EDR> Avian influenza (116): Europe (Russia) zoo, wild bird, backyard, HPAI H5N1, OIE
  Mon, 20 Sep 2021 15:46:50 -0400
  Avian Influenza H5N1 -- Russia
  Summary
  Report type: immediate notification
  Started: 27 Aug 2021
  Confirmed: 2 Sep 2021
  Reported: 15 Sep 2021
  Reason for notification: recurrence
  Last occurrence: 13 Dec 2020
  Causal agent: highly pathogenic avian influenza virus
  Serotype: H5N1
  Nature of diagnosis: clinical, laboratory
  This event pertains to a defined zone within the country.
  New outbreaks (3)
  Summary of outbreaks
  Total outbreaks (3)
  Outbreak location 1: Zateryanny mir, Chelyabinsk gorsovet,


• PRO/AH/EDR> Avian influenza, human (20): Cambodia (SI) H9N2
  Sun, 19 Sep 2021 19:23:42 -0400
  Avian Influenza -- Cambodia
  Abstract
  ---------
  In February 2021, routine sentinel surveillance for influenza-like illness in Cambodia detected a human avian influenza A(H9N2) virus infection. Investigations identified no recent H9N2 virus infections in 43 close contacts. One chicken sample from the infected child's house was positive for H9N2 virus and genetically similar to the human virus.
  --
  Communicated by:
  Jurre Siegers
  Institute Pasteur du Cambodge
  
  [ProMED thanks Jurre Siegers for sharing the early

• The role of human bocavirus as an agent of community-acquired pneumonia in children under 5 years of age in Fortaleza, Ceará (Northeast Brazil) Sat, 06 Aug 2022 06:00:00 -0400
  The human bocavirus (HBoV) is an agent of upper and lower respiratory infections, affecting mainly children under 5 years of age. Community-acquired pneumonia (CAP) is an important public health problem in developing countries, representing one of the main causes of hospitalizations and deaths in children. The aim of this study was to describe the prevalence of HBoV and the clinical and epidemiological characteristics in children diagnosed with CAP. For this purpose, nasopharyngeal aspirates...
• Immunogenicity and safety of a SARS-CoV-2 inactivated vaccine (CoronaVac) co-administered with an inactivated quadrivalent influenza vaccine: A randomized, open-label, controlled study in healthy adults aged 18 to 59 years in China Sat, 06 Aug 2022 06:00:00 -0400
  CONCLUSION: Co-administration of inactivated COVID-19 vaccine and seasonal influenza vaccine, especially the administration regimen that the seasonal influenza vaccine co-administered with the first dose of the inactivated COVID-19 vaccine, would be feasible.
• Functional characterization of bat IRF1 in IFN induction Sat, 06 Aug 2022 06:00:00 -0400
  Bats are natural hosts for various zoonotic viral diseases. However, they rarely show signs of disease infection with such viruses. During viral infection, members of the IRFs family induce the production of IFNβ and exert antiviral effects. However, the functions of bat IRFs remain unclear. In this study, the Tadarida brasiliensis IRF1 (TbIRF1) gene was first cloned and a series of bioinformatics studies were conducted. Results showed that bat IRF1 protein sequence showed a low similarity with...
• Understanding the rebound of influenza in the post COVID19 pandemic period holds important clues for epidemiology and control Sat, 06 Aug 2022 06:00:00 -0400
  No abstract
• Is the UK prepared for seasonal influenza in 2022-23 and beyond? Sat, 06 Aug 2022 06:00:00 -0400
  No abstract
• Associations between maternal reports of periconceptional fever from miscellaneous causes and structural birth defects Sat, 06 Aug 2022 06:00:00 -0400
  CONCLUSION: Our data suggests fever itself or other physiologic changes associated with many infections are associated with some birth defects. Women who are pregnant or planning to become pregnant may want to consider speaking with their healthcare provider about the best ways to avoid infections that may cause fever and for guidance on how to treat fevers during pregnancy.
• Immunogenicity and safety of an inactivated SARS-CoV-2 vaccine (Sinopharm BBIBP-CorV) coadministered with quadrivalent split-virion inactivated influenza vaccine and 23-valent pneumococcal polysaccharide vaccine in China: A multicentre, non-inferiority, open-label, randomised, controlled, phase 4 trial Fri, 05 Aug 2022 06:00:00 -0400
  CONCLUSIONS: The coadministration of the inactivated SARS-CoV-2 vaccine and IIV4/PPV23 is safe with satisfactory immunogenicity. This study is registered with ClinicalTrials.gov, NCT04790851.
• Evaluation of PCR-Based Hemagglutinin Subtyping as a Tool to aid in Surveillance of Avian Influenza viruses in Migratory Wild Birds Fri, 05 Aug 2022 06:00:00 -0400
  The surveillance of migratory wild birds (MWBs) for avian influenza virus (AIV) allows detecting the emergence of highly pathogenic AIV that can infect domestic poultry and mammals, new subtypes, and antigenic/genetic variants. The current AIV surveillance system for MWBs in the United States is based on virus isolation (VI) followed by sequencing isolates. This system primarily focuses on the early detection of H5 and H7 AIVs. However, it is suboptimal in assessing diverse AIV subtypes at any...
• Analysis of the responsible site for favipiravir resistance in RNA-dependent RNA polymerase of influenza virus A/PR/8/34 (H1N1) using site-directed mutagenesis Fri, 05 Aug 2022 06:00:00 -0400
  Favipiravir (T-705, 6-fluoro-3-hydroxy-2-pyrazinecarboxamide) selectively and strongly inhibits the replication of influenza virus in vitro and in vivo. Favipiravir is converted to favipiravir-4-ribofuranosyl-5-triphosphate (favipiravir RTP) by intracellular enzymes and functions as a nucleotide analog to selectively inhibit RNA-dependent RNA polymerase (RdRP) of influenza virus. Our previous experiments failed in an attempt to obtain a favipiravir-resistant influenza virus in vitro using...
• The impact of temporary methotrexate discontinuation for 1 week versus 2 weeks on seasonal influenza vaccination in patients with rheumatoid arthritis Fri, 05 Aug 2022 06:00:00 -0400
  CONCLUSIONS: Temporarily discontinuing MTX for 1 week is non-inferior to MTX discontinuation for 2 weeks after vaccination to induce a satisfactory vaccine response to a seasonal influenza vaccine in patients with RA on a stable dose of MTX. This article is protected by copyright. All rights reserved.